Anti-KCNH5 antibody (C-Term) (STJ13101621)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from the c-terminal of human KCNH5 (Potassium voltage-gated channel subfamily H member 5) conjugated to an immunogenic carrier protein was used as the antigen.
General Information
| Short Description | Rabbit polyclonal anti-KCNH5 (C-Term) for use in IHC and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB. A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | KCNH5 |
| Gene ID | 27133 |
| Uniprot ID | KCNH5_HUMAN |
| Immunogen | A synthetic peptide from the c-terminal of human KCNH5 (Potassium voltage-gated channel subfamily H member 5) conjugated to an immunogenic carrier protein was used as the antigen. |
| Immunogen Region | C-Term |
| Specificity | Specific for KCNH5. |
Additional Info
| Function | Pore-forming (alpha) subunit of a voltage-gated delayed rectifier potassium channel that mediates outward-rectifying potassium currents which, on depolarization, reaches a steady-state level and do not inactivate. The kinetic is characterized by a slow activation time course and a small voltage dependence of the activation time constants, therefore, starts to open at more negative voltages. The activation kinetics depend on the prepulse potential and external divalent cation concentration. The time course of activation is biphasic with a fast and a slowly activating current component. With negative prepulses, the current activation is delayed and slowed down several fold, whereas more positive prepulses speed up activation, therefore the activation rate depends on holding potential. |
| Protein Name | Voltage-Gated Delayed Rectifier Potassium Channel Kcnh5Ether-A-Go-Go Potassium Channel 2Heag2Potassium Voltage-Gated Channel Subfamily H Member 5Voltage-Gated Potassium Channel Subunit Kv10.2 |
| Database Links | Reactome: R-HSA-1296072 |
| Cellular Localisation | MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Voltage-Gated Delayed Rectifier Potassium Channel Kcnh5 antibodyAnti-Ether-A-Go-Go Potassium Channel 2 antibodyAnti-Heag2 antibodyAnti-Potassium Voltage-Gated Channel Subfamily H Member 5 antibodyAnti-Voltage-Gated Potassium Channel Subunit Kv10.2 antibodyAnti-KCNH5 antibodyAnti-EAG2 antibody |
Information sourced from Uniprot.org