• Immunohistochemistryt analysis of paraffin-embedded human brain, using KCNC1 Antibody. The lane on the right is blocked with the KCNC1 peptide.
  • Western blot analysis of K562 cells using KV3.1 Polyclonal Antibody
  • Western blot analysis of KCNC1 Antibody. The lane on the right is blocked with the KCNC1 peptide.
  • Western blot analysis of various cells using KV3.1 Polyclonal Antibody

Anti-KCNC1 antibody (190-270 aa) (STJ93875)

SKU:
STJ93875

Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Potassium voltage-gated channel subfamily C member 1 (190-270 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:5000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: KCNC1
Gene ID: 3746
Uniprot ID: KCNC1_HUMAN
Immunogen Region: 190-270 aa
Specificity: KV3.1 Polyclonal Antibody detects endogenous levels of KV3.1 protein.
Immunogen: Synthesized peptide derived from KV3.1 at the amino acid range 190-270
Function Voltage-gated potassium channel that plays an important role in the rapid repolarization of fast-firing brain neurons. The channel opens in response to the voltage difference across the membrane, forming a potassium-selective channel through which potassium ions pass in accordance with their electrochemical gradient. Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNC2, and possibly other family members as well. Contributes to fire sustained trains of very brief action potentials at high frequency in pallidal neurons.
Protein Name Potassium Voltage-Gated Channel Subfamily C Member 1
Ngk2
Voltage-Gated Potassium Channel Subunit Kv3.1
Voltage-Gated Potassium Channel Subunit Kv4
Database Links Reactome: R-HSA-1296072
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Cell Projection
Axon
Presynaptic Cell Membrane
Localizes In Parallel Fiber Membranes
Distributed On The Perisynaptic And Extrasynaptic Membranes Away From The Active Zones
Alternative Antibody Names Anti-Potassium Voltage-Gated Channel Subfamily C Member 1 antibody
Anti-Ngk2 antibody
Anti-Voltage-Gated Potassium Channel Subunit Kv3.1 antibody
Anti-Voltage-Gated Potassium Channel Subunit Kv4 antibody
Anti-KCNC1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance