| Host: |
Rabbit |
| Applications: |
IHC/WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-KCNA3 (450-500 aa) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Lyophilised |
| Purification: |
IgG purified |
| Dilution Range: |
IHC, WB. A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Storage Instruction: |
Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: |
KCNA3 |
| Gene ID: |
3738 |
| Uniprot ID: |
KCNA3_HUMAN |
| Immunogen Region: |
450-500 aa |
| Specificity: |
Specific for KCNA3. |
| Immunogen: |
A synthetic peptide from aa region 450-500 of human KCNA3 conjugated to an immunogenic carrier protein was used as the antigen. |
| Function | Isoform 1: Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. Isoform 2: Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. Isoform 3: Lacks voltage-gated potassium channel activity. |
| Protein Name | Potassium Voltage-Gated Channel Subfamily A Member 3Hgk5Hlk3Hpcn3Voltage-Gated K(+ Channel HukiiiVoltage-Gated Potassium Channel Subunit Kv1.3 |
| Database Links | Reactome: R-HSA-1296072 |
| Cellular Localisation | Isoform 1: Cell MembraneMulti-Pass Membrane ProteinIsoform 2: Cell MembraneIsoform 3: CytoplasmPerinuclear Region |
| Alternative Antibody Names | Anti-Potassium Voltage-Gated Channel Subfamily A Member 3 antibodyAnti-Hgk5 antibodyAnti-Hlk3 antibodyAnti-Hpcn3 antibodyAnti-Voltage-Gated K(+ Channel Hukiii antibodyAnti-Voltage-Gated Potassium Channel Subunit Kv1.3 antibodyAnti-KCNA3 antibodyAnti-HGK5 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
