Anti-KAZN antibody (125-175) (STJA0006365)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human KAZRN AA range: 125-175
General Information
| Short Description | Rabbit polyclonal anti-Kazrin (125-175) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:1000-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | KAZN |
| Gene ID | 23254 |
| Uniprot ID | KAZRN_HUMAN |
| Immunogen | Synthesized peptide derived from human KAZRN AA range: 125-175 |
| Immunogen Region | 125-175 |
| Specificity | This antibody detects endogenous levels of human KAZRN |
Additional Info
| Function | Component of the cornified envelope of keratinocytes. May be involved in the interplay between adherens junctions and desmosomes. The function in the nucleus is not known. |
| Protein Name | Kazrin |
| Database Links | Reactome: R-HSA-6809371 |
| Cellular Localisation | CytoplasmCytoskeletonIsoform 2: CytoplasmCell JunctionDesmosomeNucleusObserved At The Apical Plasma Membrane Of KeratinocytesPartially Colocalizes With Ppl And Dp At DesmosomesAnd With Pp At The Interdesmosomal Plasma MembraneColocalizes With Cortical Actin-Based Membrane StructuresIsoform 3: CytoplasmIsoform 4: Cytoplasm |
| Alternative Antibody Names | Anti-Kazrin antibodyAnti-KAZN antibodyAnti-C1orf196 antibodyAnti-KAZ antibodyAnti-KIAA1026 antibodyAnti-HRIHFB2003 antibody |
Information sourced from Uniprot.org