Anti-KATNAL1 antibody (STJA0009578)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human KATNAL1
General Information
| Short Description | Rabbit polyclonal anti-Katanin p60 ATPase-containing subunit A-like 1 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | KATNAL1 |
| Gene ID | 84056 |
| Uniprot ID | KATL1_HUMAN |
| Immunogen | Synthesized peptide derived from human KATNAL1 |
| Specificity | This antibody detects endogenous levels of KATNAL1 at Human, Mouse, Rat |
Additional Info
| Function | Regulates microtubule dynamics in Sertoli cells, a process that is essential for spermiogenesis and male fertility. Severs microtubules in an ATP-dependent manner, promoting rapid reorganization of cellular microtubule arrays. Has microtubule-severing activity in vitro. |
| Protein Name | Katanin P60 Atpase-Containing Subunit A-Like 1Katanin P60 Subunit A-Like 1P60 Katanin-Like 1 |
| Database Links | |
| Cellular Localisation | CytoplasmCytoskeletonSpindle PoleSpindleColocalizes With Microtubules Throughout The Basal And Adluminal Compartments Of Sertoli CellsLocalizes Within The CytoplasmPartially Overlapping With MicrotubulesIn Interphase And To The Mitotic Spindle And Spindle Poles During Mitosis |
| Alternative Antibody Names | Anti-Katanin P60 Atpase-Containing Subunit A-Like 1 antibodyAnti-Katanin P60 Subunit A-Like 1 antibodyAnti-P60 Katanin-Like 1 antibodyAnti-KATNAL1 antibody |
Information sourced from Uniprot.org