Anti-KAL1 antibody (200-300) (STJ118817)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal KAL1 (200-300) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ANOS1 |
| Gene ID | 3730 |
| Uniprot ID | KALM_HUMAN |
| Immunogen Region | 200-300 |
| Immunogen Sequence | LEVKWSSKFNISIEPVIYVV QRRWNYGIHPSEDDATHWQT VAQTTDERVQLTDIRPSRWY QFRVAAVNVHGTRGFTAPSK HFRSSKDPSAPPAPANLRLA N |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 200-300 of human KAL1 (NP_000207.2). |
Additional Info
| Tissue Specificity | Expressed in the cerebellum (at protein level). |
| Post Translational Modifications | N-glycosylated. May be proteolytically cleaved at the cell surface and released from the cell surface. |
| Function | Has a dual branch-promoting and guidance activity, which may play an important role in the patterning of mitral and tufted cell collaterals to the olfactory cortex. Chemoattractant for fetal olfactory epithelial cells. |
| Protein Name | Anosmin-1Adhesion Molecule-Like X-LinkedKallmann Syndrome Protein |
| Database Links | Reactome: R-HSA-190373Reactome: R-HSA-5654726 |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinSecretedProteolytic Cleavage May Release It From The Cell Surface Into The Extracellular Space |
| Alternative Antibody Names | Anti-Anosmin-1 antibodyAnti-Adhesion Molecule-Like X-Linked antibodyAnti-Kallmann Syndrome Protein antibodyAnti-ANOS1 antibodyAnti-ADMLX antibodyAnti-KAL antibodyAnti-KAL1 antibodyAnti-KALIG1 antibody |
Information sourced from Uniprot.org