Anti-JUNB antibody (1-200) (STJ116777)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal JUNB (1-200) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:100-1:500ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | JUNB |
| Gene ID | 3726 |
| Uniprot ID | JUNB_HUMAN |
| Immunogen Region | 1-200 |
| Immunogen Sequence | MCTKMEQPFYHDDSYTATGY GRAPGGLSLHDYKLLKPSLA VNLADPYRSLKAPGARGPGP EGGGGGSYFSGQGSDTGASL KLASSELERLIVPNSNGVIT TTPTPPGQYFYPRGGGSGGG AGGAGGGVTEEQEGFADGFV KALDDLHKMNHVTPPNVSLG ATGGPPAGPGGVYAGPEPPP VYTNLSSYSPASASSGGAGA |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human JunB (NP_002220.1). |
Additional Info
| Post Translational Modifications | Ubiquitinated by ITCH, leading to its degradation. |
| Function | Transcription factor involved in regulating gene activity following the primary growth factor response. Binds to the DNA sequence 5'-TGAGCTCA-3'. Heterodimerizes with proteins of the FOS family to form an AP-1 transcription complex, thereby enhancing its DNA binding activity to an AP-1 consensus sequence and its transcriptional activity. |
| Protein Name | Transcription Factor JunbTranscription Factor Ap-1 Subunit Junb |
| Database Links | Reactome: R-HSA-2173796Reactome: R-HSA-6785807Reactome: R-HSA-9031628Reactome: R-HSA-9725371 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Transcription Factor Junb antibodyAnti-Transcription Factor Ap-1 Subunit Junb antibodyAnti-JUNB antibody |
Information sourced from Uniprot.org