| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Junctophilin-1 is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
JPH1 |
| Gene ID: |
56704 |
| Uniprot ID: |
JPH1_HUMAN |
| Specificity: |
This antibody detects endogenous levels of JPH1 at Human, Mouse |
| Immunogen: |
Synthesized peptide derived from human JPH1 |
| Function | Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. JPH1 contributes to the construction of the skeletal muscle triad by linking the t-tubule (transverse-tubule) and SR (sarcoplasmic reticulum) membranes. |
| Protein Name | Junctophilin-1Jp-1Junctophilin Type 1 |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinEndoplasmic Reticulum MembraneSingle-Pass Type Iv Membrane ProteinSarcoplasmic Reticulum MembraneLocalized Predominantly On The Plasma MembraneThe Transmembrane Domain Is Anchored In Endoplasmic/Sarcoplasmic Reticulum MembraneWhile The N-Terminal Part Associates With The Plasma MembraneIn Skeletal Muscle CellsIt Is Predominantly Localized At The Junction Of The A And I Bands |
| Alternative Antibody Names | Anti-Junctophilin-1 antibodyAnti-Jp-1 antibodyAnti-Junctophilin Type 1 antibodyAnti-JPH1 antibodyAnti-JP1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
