Anti-JMJD4 antibody (1-463) (STJ110299)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal JMJD4 (1-463) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | JMJD4 |
| Gene ID | 65094 |
| Uniprot ID | JMJD4_HUMAN |
| Immunogen Region | 1-463 |
| Immunogen Sequence | MRAGPEPQALAGQKRGALRL LVPRLVLTVSAPAEVRRRVL RPVLSWMDRETRALADSHFR GLGVDVPGVGQAPGRVAFVS EPGAFSYADFVRGFLLPNLP CVFSSAFTQGWGSRRRWVTP AGRPDFDHLLRTYGDVVVPV ANCGVQEYNSNPKEHMTLRD YITYWKEYIQAGYSSPRGCL YLKDWHLCRDFPVEDVFTLP VYFSSDWLNEFWDALDVDDY RFVYAGPAGSWSPFHADIF |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-463 of human JMJD4 (NP_075383.2). |
Additional Info
| Function | Catalyzes the 2-oxoglutarate and iron-dependent C4-lysyl hydroxylation of ETF1 at 'Lys-63' thereby promoting the translational termination efficiency of ETF1. |
| Protein Name | 2-Oxoglutarate And Iron-Dependent Oxygenase Jmjd4Jmjc Domain-Containing Protein 4Jumonji Domain-Containing Protein 4Lysyl-Hydroxylase Jmjd4 |
| Database Links | Reactome: R-HSA-9629569 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-2-Oxoglutarate And Iron-Dependent Oxygenase Jmjd4 antibodyAnti-Jmjc Domain-Containing Protein 4 antibodyAnti-Jumonji Domain-Containing Protein 4 antibodyAnti-Lysyl-Hydroxylase Jmjd4 antibodyAnti-JMJD4 antibody |
Information sourced from Uniprot.org