Anti-JAZF1 antibody (57-107 aa) (STJ195376)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human JAZF1 at the amino acid range 57-107
General Information
| Short Description | Rabbit polyclonal anti-Juxtaposed with another zinc finger protein 1 (57-107 aa) for use in WB and IHC in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC-P 1:50-300 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | JAZF1 |
| Gene ID | 221895 |
| Uniprot ID | JAZF1_HUMAN |
| Immunogen | Synthesized peptide derived from the human JAZF1 at the amino acid range 57-107 |
| Immunogen Region | 57-107 aa |
| Specificity | This antibody detects endogenous levels of JAZF1 at Human/Mouse |
Additional Info
| Function | Acts as a transcriptional corepressor of orphan nuclear receptor NR2C2. Inhibits expression of the gluconeogenesis enzyme PCK2 through inhibition of NR2C2 activity. Also involved in transcriptional activation of NAMPT by promoting expression of PPARA and PPARD. Plays a role in lipid metabolism by suppressing lipogenesis, increasing lipolysis and decreasing lipid accumulation in adipose tissue. Plays a role in glucose homeostasis by improving glucose metabolism and insulin sensitivity. |
| Protein Name | Juxtaposed With Another Zinc Finger Protein 1Tak1-Interacting Protein 27Zinc Finger Protein 802 |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Juxtaposed With Another Zinc Finger Protein 1 antibodyAnti-Tak1-Interacting Protein 27 antibodyAnti-Zinc Finger Protein 802 antibodyAnti-JAZF1 antibodyAnti-TIP27 antibodyAnti-ZNF802 antibody |
Information sourced from Uniprot.org