Anti-JAGN1 antibody (111-161 aa) (STJ197750)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human JAGN1 at the amino acid range 111-161
General Information
| Short Description | Rabbit polyclonal anti-Protein jagunal homolog 1 (111-161 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:1000-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | JAGN1 |
| Gene ID | 84522 |
| Uniprot ID | JAGN1_HUMAN |
| Immunogen | Synthesized peptide derived from the human JAGN1 at the amino acid range 111-161 |
| Immunogen Region | 111-161 aa |
| Specificity | This antibody detects endogenous levels of human JAGN1 |
Additional Info
| Function | Endoplasmic reticulum transmembrane protein involved in vesicle-mediated transport, which is required for neutrophil function. Required for vesicle-mediated transport.it is however unclear whether it is involved in early secretory pathway or intracellular protein transport. Acts as a regulator of neutrophil function, probably via its role in vesicle-mediated transport: required for defense against fungal pathogens and for granulocyte colony-stimulating factor (GM-CSF) signaling pathway.possibly by regulating glycosylation and/or targeting of proteins contributing to the viability and migration of neutrophils. |
| Protein Name | Protein Jagunal Homolog 1 |
| Database Links | |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Protein Jagunal Homolog 1 antibodyAnti-JAGN1 antibody |
Information sourced from Uniprot.org