Anti-JAG2 antibody (24-200) (STJ116460)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal JAG2 (24-200) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | JAG2 |
| Gene ID | 3714 |
| Uniprot ID | JAG2_HUMAN |
| Immunogen Region | 24-200 |
| Immunogen Sequence | ARPMGYFELQLSALRNVNGE LLSGACCDGDGRTTRAGGCG HDECDTYVRVCLKEYQAKVT PTGPCSYGHGATPVLGGNSF YLPPAGAAGDRARARARAGG DQDPGLVVIPFQFAWPRSFT LIVEAWDWDNDTTPNEELLI ERVSHAGMINPEDRWKSLHF SGHVAHLELQIRVRCDE |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 24-200 of human JAG2 (NP_002217.3). |
Additional Info
| Tissue Specificity | Expressed in heart, placenta and skeletal muscle and to a lesser extent in pancreas. Very low expression in brain, lung, liver and kidney. |
| Function | Putative Notch ligand involved in the mediation of Notch signaling. Involved in limb development. |
| Protein Name | Protein Jagged-2Jagged2Hj2 |
| Database Links | Reactome: R-HSA-2122948Reactome: R-HSA-2644606Reactome: R-HSA-2660826Reactome: R-HSA-2691232Reactome: R-HSA-2894862Reactome: R-HSA-2979096Reactome: R-HSA-9013507 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Protein Jagged-2 antibodyAnti-Jagged2 antibodyAnti-Hj2 antibodyAnti-JAG2 antibody |
Information sourced from Uniprot.org