Anti-JAG2 antibody (24-200) (STJ116460)

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STJ116460
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Host: Rabbit
Applications: WB/IF/ICC/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:1000
IF/ICC:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: JAG2
Gene ID: 3714
Uniprot ID: JAG2_HUMAN
Immunogen Region: 24-200
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 24-200 of human JAG2 (NP_002217.3).
Immunogen Sequence: ARPMGYFELQLSALRNVNGE LLSGACCDGDGRTTRAGGCG HDECDTYVRVCLKEYQAKVT PTGPCSYGHGATPVLGGNSF YLPPAGAAGDRARARARAGG DQDPGLVVIPFQFAWPRSFT LIVEAWDWDNDTTPNEELLI ERVSHAGMINPEDRWKSLHF SGHVAHLELQIRVRCDE
Tissue Specificity Expressed in heart, placenta and skeletal muscle and to a lesser extent in pancreas. Very low expression in brain, lung, liver and kidney.
Function Putative Notch ligand involved in the mediation of Notch signaling. Involved in limb development.
Protein Name Protein Jagged-2
Jagged2
Hj2
Database Links Reactome: R-HSA-2122948
Reactome: R-HSA-2644606
Reactome: R-HSA-2660826
Reactome: R-HSA-2691232
Reactome: R-HSA-2894862
Reactome: R-HSA-2979096
Reactome: R-HSA-9013507
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Protein Jagged-2 antibody
Anti-Jagged2 antibody
Anti-Hj2 antibody
Anti-JAG2 antibody

Information sourced from Uniprot.org