Anti-200 Neurofilament antibody (150-200 aa) (STJ13100202)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from aa region 150-200 of human 200 Neurofilament conjugated to blue carrier protein was used as the antigen. The peptide is homologous in mouse and rat.
General Information
| Short Description | Rabbit polyclonal anti-200 Neurofilament (150-200 aa) for use in IHC and WB in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB. A dilution of 1:1000 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | NEFH |
| Gene ID | 4744 |
| Uniprot ID | NFH_HUMAN |
| Immunogen | A synthetic peptide from aa region 150-200 of human 200 Neurofilament conjugated to blue carrier protein was used as the antigen. The peptide is homologous in mouse and rat. |
| Immunogen Region | 150-200 aa |
| Specificity | Specific for Neurofilament heavy polypeptide. |
Additional Info
| Function | Neurofilaments usually contain three intermediate filament proteins: NEFL, NEFM, and NEFH which are involved in the maintenance of neuronal caliber. NEFH has an important function in mature axons that is not subserved by the two smaller NF proteins. May additionally cooperate with the neuronal intermediate filament proteins PRPH and INA to form neuronal filamentous networks. |
| Protein Name | Neurofilament Heavy PolypeptideNf-H200 Kda Neurofilament ProteinNeurofilament Triplet H Protein |
| Database Links | |
| Cellular Localisation | CytoplasmCytoskeletonCell ProjectionAxon |
| Alternative Antibody Names | Anti-Neurofilament Heavy Polypeptide antibodyAnti-Nf-H antibodyAnti-200 Kda Neurofilament Protein antibodyAnti-Neurofilament Triplet H Protein antibodyAnti-NEFH antibodyAnti-KIAA0845 antibodyAnti-NFH antibody |
Information sourced from Uniprot.org