Anti-ITSN2 antibody (1125-1175 aa) (STJ192904)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein at the amino acid range 1125-1175
General Information
| Short Description | Rabbit polyclonal anti-Intersectin-2 (1125-1175 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ITSN2 |
| Gene ID | 50618 |
| Uniprot ID | ITSN2_HUMAN |
| Immunogen | Synthesized peptide derived from part of the human protein at the amino acid range 1125-1175 |
| Immunogen Region | 1125-1175 aa |
| Specificity | ITSN2 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Adapter protein that may provide indirect link between the endocytic membrane traffic and the actin assembly machinery. May regulate the formation of clathrin-coated vesicles (CCPs). Seems to be involved in CCPs maturation including invagination or budding. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR). Plays a role in dendrite formation by melanocytes. |
| Protein Name | Intersectin-2Sh3 Domain-Containing Protein 1bSh3p18Sh3p18-Like Wasp-Associated Protein |
| Database Links | Reactome: R-HSA-8856825Reactome: R-HSA-8856828Reactome: R-HSA-9013420 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Intersectin-2 antibodyAnti-Sh3 Domain-Containing Protein 1b antibodyAnti-Sh3p18 antibodyAnti-Sh3p18-Like Wasp-Associated Protein antibodyAnti-ITSN2 antibodyAnti-KIAA1256 antibodyAnti-SH3D1B antibodyAnti-SWAP antibody |
Information sourced from Uniprot.org