• Western blot analysis of HeLa, using ITPR3 rabbit polyclonal antibody (STJ114939) at 1:2000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% non-fat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
  • Immunofluorescence analysis of NIH-3T3 cells using ITPR3 antibody (STJ114939) at dilution of 1:100. Blue: DAPI for nuclear staining.
  • Immunoprecipitation analysis of 300 Mu g extracts of Hela cells using 3 Mu g ITPR3 antibody (STJ114939). Western blot was performed from the immunoprecipitate using ITPR3 antibody (STJ114939) at a dilution of 1:1000.

Anti-ITPR3 antibody (1630-1870) (STJ114939)

SKU:
STJ114939

£169.50 - £449.50
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Host: Rabbit
Applications: WB/IF/IP
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-ITPR3 (1630-1870) is suitable for use in Western Blot, Immunofluorescence and Immunoprecipitation research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:1000-1:5000
IF/ICC 1:50-1:200
IP 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ITPR3
Gene ID: 3710
Uniprot ID: ITPR3_HUMAN
Immunogen Region: 1630-1870
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1630-1870 of human ITPR3 (NP_002215.2).
Immunogen Sequence: EGSEAYQRCESGGFLSKLIQ HTKDLMESEEKLCIKVLRTL QQMLLKKTKYGDRGNQLRKM LLQNYLQNRKSTSRGDLPDP IGTGLDPDWSAIAATQCRLD KEGATKLVCDLITSTKNEKI FQESIGLAIHLLDGGNTEIQ KSFHNLMMSDKKSERFFKVL HDRMKRAQQETKSTVAVNMN DLGSQPHEDREPVDPTTKGR VASFSIPGSSSRYSLGPSLR RGHEVSERVQSSEMGTSVL
Tissue Specificity Expressed in intestinal crypt and villus epithelial cells.
Post Translational Modifications Phosphorylated on tyrosine residues. Phosphorylated by AKT1 on serine and/or threonine residues.
Function Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. Involved in cellular calcium ion homeostasis.
Protein Name Inositol 1 -4 -5-Trisphosphate Receptor Type 3
Ip3 Receptor Isoform 3
Ip3r 3
Insp3r3
Type 3 Inositol 1 -4 -5-Trisphosphate Receptor
Type 3 Insp3 Receptor
Database Links Reactome: R-HSA-112043
Reactome: R-HSA-114508
Reactome: R-HSA-139853
Reactome: R-HSA-1489509
Reactome: R-HSA-2029485
Reactome: R-HSA-2871809
Reactome: R-HSA-381676
Reactome: R-HSA-4086398
Reactome: R-HSA-422356
Reactome: R-HSA-5218921
Reactome: R-HSA-5578775
Reactome: R-HSA-5607763
Reactome: R-HSA-9664323
Reactome: R-HSA-9717207
Reactome: R-HSA-983695
Cellular Localisation Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Inositol 1 -4 -5-Trisphosphate Receptor Type 3 antibody
Anti-Ip3 Receptor Isoform 3 antibody
Anti-Ip3r 3 antibody
Anti-Insp3r3 antibody
Anti-Type 3 Inositol 1 -4 -5-Trisphosphate Receptor antibody
Anti-Type 3 Insp3 Receptor antibody
Anti-ITPR3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance