Anti-ITPR2 antibody (STJA0004426)

SKU:
STJA0004426

Current Stock:
Host: Rabbit
Applications: IHC/ELISA
Reactivity: Human/Mouse/Rat
Note: FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Inositol 1-4-5-Trisphosphate Receptor Type 2 is suitable for use in Immunohistochemistry and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification: Antigen affinity purification
Concentration: 1.86 mg/mL
Dilution Range: IHC 1:50-1:300
Storage Instruction: Store at-20°C for long term, and avoid freeze-thaw cycles.
Gene Symbol: ITPR2
Gene ID: 3709
Uniprot ID: ITPR2_HUMAN
Immunogen: Synthetic peptide of human ITPR2
Tissue Specificity Isoform Short is found in skeletal muscle and heart.
Post Translational Modifications Phosphorylation by cAMP-dependent PKA on Ser-937 increases calcium release.
Function Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. This release is regulated by cAMP both dependently and independently of PKA.
Protein Name Inositol 1 -4 -5-Trisphosphate Receptor Type 2
Ip3 Receptor Isoform 2
Ip3r 2
Insp3r2
Type 2 Inositol 1 -4 -5-Trisphosphate Receptor
Type 2 Insp3 Receptor
Database Links Reactome: R-HSA-112043
Reactome: R-HSA-114508
Reactome: R-HSA-139853
Reactome: R-HSA-1489509
Reactome: R-HSA-2029485
Reactome: R-HSA-2871809
Reactome: R-HSA-381676
Reactome: R-HSA-4086398
Reactome: R-HSA-422356
Reactome: R-HSA-5218921
Reactome: R-HSA-5578775
Reactome: R-HSA-5607763
Reactome: R-HSA-9664323
Reactome: R-HSA-983695
Cellular Localisation Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Inositol 1 -4 -5-Trisphosphate Receptor Type 2 antibody
Anti-Ip3 Receptor Isoform 2 antibody
Anti-Ip3r 2 antibody
Anti-Insp3r2 antibody
Anti-Type 2 Inositol 1 -4 -5-Trisphosphate Receptor antibody
Anti-Type 2 Insp3 Receptor antibody
Anti-ITPR2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance