Anti-ITGB5 antibody (24-490 aa) [S5106RM] (STJ11105106)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal Integrin Beta-5 (24-490 aa) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S5106RM |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1000-1:4000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ITGB5 |
| Gene ID | 3693 |
| Uniprot ID | ITB5_HUMAN |
| Immunogen Region | 24-490 aa |
| Immunogen Sequence | GLNICTSGSATSCEECLLIH PKCAWCSKEDFGSPRSITSR CDLRANLVKNGCGGEIESPA SSFHVLRSLPLSSKGSGSAG WDVIQMTPQEIAVNLRPGDK TTFQLQVRQVEDYPVDLYYL MDLSLSMKDDLDNIRSLGTK LAEEMRKLTSNFRLGFGSFV DKDISPFSYTAPRYQTNPCI GYKLFPNCVPSFGFRHLLPL TDRVDSFNEEVRKQRVSRNR DAPEGGFDAVLQAAVCKEK |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 24-490 of human Integrin Beta 5/ITGB5. (NP_002204.2). |
Additional Info
| Function | Integrin alpha-V/beta-5 (ITGAV:ITGB5) is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligand. (Microbial infection) Integrin ITGAV:ITGB5 acts as a receptor for adenovirus type C. |
| Protein Name | Integrin Beta-5 |
| Database Links | Reactome: R-HSA-1236973Reactome: R-HSA-2129379Reactome: R-HSA-216083Reactome: R-HSA-2173789Reactome: R-HSA-3000170Reactome: R-HSA-3000178Reactome: R-HSA-445355 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Integrin Beta-5 antibodyAnti-ITGB5 antibody |
Information sourced from Uniprot.org