Anti-ITGA2 antibody (1100-1181 aa) [R09-7C3] (STJA0014704)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human Integrin alpha 2
General Information
| Short Description | Rabbit monoclonal anti-Integrin alpha 2 (1100-1181 aa) for use in WB, IHC-P, ICC, IF, IP and FC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ICC/IF/IP/FC |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R09-7C3 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Chromatography |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100IF 1:50-1:200IP 1:100FC 1:50-1:100 |
| Formulation | Liquid in PBS pH7.4, 150mM NaCl, 0.02% Sodium Azide and 50% Glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | ITGA2 |
| Gene ID | 3673 |
| Uniprot ID | ITA2_HUMAN |
| Immunogen | A synthesized peptide derived from human Integrin alpha 2 |
| Immunogen Region | 1100-1181 aa |
Additional Info
| Function | Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. (Microbial infection) Integrin ITGA2:ITGB1 acts as a receptor for Human rotavirus A. (Microbial infection) Integrin ITGA2:ITGB1 acts as a receptor for Human echoviruses 1 and 8. |
| Protein Name | Integrin Alpha-2Cd49 Antigen-Like Family Member BCollagen ReceptorPlatelet Membrane Glycoprotein IaGpiaVla-2 Subunit AlphaCd Antigen Cd49b |
| Database Links | Reactome: R-HSA-216083Reactome: R-HSA-3000157Reactome: R-HSA-3000170Reactome: R-HSA-3000178Reactome: R-HSA-447041Reactome: R-HSA-75892Reactome: R-HSA-8874081Reactome: R-HSA-9926550 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Integrin Alpha-2 antibodyAnti-Cd49 Antigen-Like Family Member B antibodyAnti-Collagen Receptor antibodyAnti-Platelet Membrane Glycoprotein Ia antibodyAnti-Gpia antibodyAnti-Vla-2 Subunit Alpha antibodyAnti-Cd Antigen Cd49b antibodyAnti-ITGA2 antibodyAnti-CD49B antibody |
Information sourced from Uniprot.org