Anti-ITGA1 antibody (29-1141) [S4928RM] (STJ11104928)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal Integrin Alpha-1 (29-1141) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S4928RM |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:10000-1:120000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ITGA1 |
| Gene ID | 3672 |
| Uniprot ID | ITA1_HUMAN |
| Immunogen Region | 29-1141 |
| Immunogen Sequence | FNVDVKNSMTFSGPVEDMFG YTVQQYENEEGKWVLIGSPL VGQPKNRTGDVYKCPVGRGE SLPCVKLDLPVNTSIPNVTE VKENMTFGSTLVTNPNGGFL ACGPLYAYRCGHLHYTTGIC SDVSPTFQVVNSIAPVQECS TQLDIVIVLDGSNSIYPWDS VTAFLNDLLERMDIGPKQTQ VGIVQYGENVTHEFNLNKYS STEEVLVAAKKIVQRGGRQT MTALGIDTARKEAFTEARG |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 29-1141 of human Integrin alpha 1 (ITGA1/CD49a) (NP_852478.1). |
Additional Info
| Function | Integrin alpha-1/beta-1 is a receptor for laminin and collagen. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. Involved in anchorage-dependent, negative regulation of EGF-stimulated cell growth. |
| Protein Name | Integrin Alpha-1Cd49 Antigen-Like Family Member ALaminin And Collagen ReceptorVla-1Cd Antigen Cd49a |
| Database Links | Reactome: R-HSA-216083Reactome: R-HSA-3000157Reactome: R-HSA-416700Reactome: R-HSA-445355Reactome: R-HSA-447041Reactome: R-HSA-75892 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Integrin Alpha-1 antibodyAnti-Cd49 Antigen-Like Family Member A antibodyAnti-Laminin And Collagen Receptor antibodyAnti-Vla-1 antibodyAnti-Cd Antigen Cd49a antibodyAnti-ITGA1 antibody |
Information sourced from Uniprot.org