• Western blot analysis of various lysates, using Integrin alpha 1 (ITGA1/CD49a) antibody (STJ11104928) at 1:100000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.

Anti-ITGA1 antibody (29-1141) [S4928RM] (STJ11104928)

SKU:
STJ11104928

£151.50 - £666.50
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Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-Integrin Alpha-1 (29-1141) is suitable for use in Western Blot research applications.
Clonality: Monoclonal
Clone ID: S4928RM
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:10000-1:120000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ITGA1
Gene ID: 3672
Uniprot ID: ITA1_HUMAN
Immunogen Region: 29-1141
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 29-1141 of human Integrin alpha 1 (ITGA1/CD49a) (NP_852478.1).
Immunogen Sequence: FNVDVKNSMTFSGPVEDMFG YTVQQYENEEGKWVLIGSPL VGQPKNRTGDVYKCPVGRGE SLPCVKLDLPVNTSIPNVTE VKENMTFGSTLVTNPNGGFL ACGPLYAYRCGHLHYTTGIC SDVSPTFQVVNSIAPVQECS TQLDIVIVLDGSNSIYPWDS VTAFLNDLLERMDIGPKQTQ VGIVQYGENVTHEFNLNKYS STEEVLVAAKKIVQRGGRQT MTALGIDTARKEAFTEARG
Function Integrin alpha-1/beta-1 is a receptor for laminin and collagen. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. Involved in anchorage-dependent, negative regulation of EGF-stimulated cell growth.
Protein Name Integrin Alpha-1
Cd49 Antigen-Like Family Member A
Laminin And Collagen Receptor
Vla-1
Cd Antigen Cd49a
Database Links Reactome: R-HSA-216083
Reactome: R-HSA-3000157
Reactome: R-HSA-416700
Reactome: R-HSA-445355
Reactome: R-HSA-447041
Reactome: R-HSA-75892
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Integrin Alpha-1 antibody
Anti-Cd49 Antigen-Like Family Member A antibody
Anti-Laminin And Collagen Receptor antibody
Anti-Vla-1 antibody
Anti-Cd Antigen Cd49a antibody
Anti-ITGA1 antibody

Information sourced from Uniprot.org

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