Anti-IRAK2 antibody (Internal) (STJ93757)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the Internal region of human IRAK-2.
General Information
| Short Description | Rabbit polyclonal anti-Interleukin-1 receptor-associated kinase-like 2 (Internal) for use in WB and IHC in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC-P 1:50-300 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | IRAK2 |
| Gene ID | 3656 |
| Uniprot ID | IRAK2_HUMAN |
| Immunogen | Synthesized peptide derived from the Internal region of human IRAK-2. |
| Immunogen Region | Internal |
| Specificity | IRAK-2 Polyclonal Antibody detects endogenous levels of IRAK-2 protein. |
Additional Info
| Function | Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. |
| Protein Name | Interleukin-1 Receptor-Associated Kinase-Like 2Irak-2 |
| Database Links | Reactome: R-HSA-166058Reactome: R-HSA-168638Reactome: R-HSA-445989Reactome: R-HSA-450302Reactome: R-HSA-450321Reactome: R-HSA-9020702Reactome: R-HSA-937042Reactome: R-HSA-937072Reactome: R-HSA-9692916Reactome: R-HSA-9705671Reactome: R-HSA-975138Reactome: R-HSA-975155Reactome: R-HSA-975163Reactome: R-HSA-975871 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Interleukin-1 Receptor-Associated Kinase-Like 2 antibodyAnti-Irak-2 antibodyAnti-IRAK2 antibody |
Information sourced from Uniprot.org