Anti-IRAK2 antibody (1-270) (STJ28718)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal IRAK2 (1-270) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | IRAK2 |
| Gene ID | 3656 |
| Uniprot ID | IRAK2_HUMAN |
| Immunogen Region | 1-270 |
| Immunogen Sequence | MACYIYQLPSWVLDDLCRNM DALSEWDWMEFASYVITDLT QLRKIKSMERVQGVSITREL LWWWGMRQATVQQLVDLLCR LELYRAAQIILNWKPAPEIR CPIPAFPDSVKPEKPLAASV RKAEDEQEEGQPVRMATFPG PGSSPARAHQPAFLQPPEED APHSLRSDLPTSSDSKDFST SIPKQEKLLSLAGDSLFWSE ADVVQATDDFNQNRKISQGT FADVYRGHRHGKPFVFKKL |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human IRAK2 (NP_001561.3). |
Additional Info
| Tissue Specificity | Expressed in spleen, thymus, prostate, lung, liver, skeletal muscle, kidney, pancreas and peripheral blood leukocytes. |
| Function | Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. |
| Protein Name | Interleukin-1 Receptor-Associated Kinase-Like 2Irak-2 |
| Database Links | Reactome: R-HSA-166058Reactome: R-HSA-168638Reactome: R-HSA-445989Reactome: R-HSA-450302Reactome: R-HSA-450321Reactome: R-HSA-9020702Reactome: R-HSA-937042Reactome: R-HSA-937072Reactome: R-HSA-9692916Reactome: R-HSA-9705671Reactome: R-HSA-975138Reactome: R-HSA-975155Reactome: R-HSA-975163Reactome: R-HSA-975871 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Interleukin-1 Receptor-Associated Kinase-Like 2 antibodyAnti-Irak-2 antibodyAnti-IRAK2 antibody |
Information sourced from Uniprot.org