• Western blot analysis of extracts of various cell lines, using IRAK2 antibody (STJ28718) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-IRAK2 antibody (1-270) (STJ28718)

SKU:
STJ28718

£112.50 - £524.50
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: IRAK2
Gene ID: 3656
Uniprot ID: IRAK2_HUMAN
Immunogen Region: 1-270
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human IRAK2 (NP_001561.3).
Immunogen Sequence: MACYIYQLPSWVLDDLCRNM DALSEWDWMEFASYVITDLT QLRKIKSMERVQGVSITREL LWWWGMRQATVQQLVDLLCR LELYRAAQIILNWKPAPEIR CPIPAFPDSVKPEKPLAASV RKAEDEQEEGQPVRMATFPG PGSSPARAHQPAFLQPPEED APHSLRSDLPTSSDSKDFST SIPKQEKLLSLAGDSLFWSE ADVVQATDDFNQNRKISQGT FADVYRGHRHGKPFVFKKL
Tissue Specificity Expressed in spleen, thymus, prostate, lung, liver, skeletal muscle, kidney, pancreas and peripheral blood leukocytes.
Function Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization.
Protein Name Interleukin-1 Receptor-Associated Kinase-Like 2
Irak-2
Database Links Reactome: R-HSA-166058
Reactome: R-HSA-168638
Reactome: R-HSA-445989
Reactome: R-HSA-450302
Reactome: R-HSA-450321
Reactome: R-HSA-9020702
Reactome: R-HSA-937042
Reactome: R-HSA-937072
Reactome: R-HSA-9692916
Reactome: R-HSA-9705671
Reactome: R-HSA-975138
Reactome: R-HSA-975155
Reactome: R-HSA-975163
Reactome: R-HSA-975871
Alternative Antibody Names Anti-Interleukin-1 Receptor-Associated Kinase-Like 2 antibody
Anti-Irak-2 antibody
Anti-IRAK2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance