Anti-IRAK1BP1 antibody (STJA0004490)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenRecombinant protein of human IRAK1BP1
General Information
| Short Description | Rabbit polyclonal antibody anti-Interleukin-1 Receptor-Associated Kinase 1-Binding Protein 1 is suitable for use in Western Blot, Immunohistochemistry and ELISA research applications. |
| Applications | WB/IHC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.4 mg/mL |
| Purification | Affinity purification |
| Dilution Range | WB 1:500-1:2000, IHC 1:50-1:200 |
| Formulation | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
| Storage Instruction | Store at-20°C for long term, and avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | IRAK1BP1 |
| Gene ID | 134728 |
| Uniprot ID | IKBP1_HUMAN |
| Immunogen | Recombinant protein of human IRAK1BP1 |
Additional Info
| Post Translational Modifications | Phosphorylation at Ser-56 and/or Ser-62 is required for full activity. Phosphorylated on at least one of Ser-235, Thr-237, Ser-242 and Thr-247 upon TNF-alpha activation, which favors nuclear translocation. |
| Function | Component of the IRAK1-dependent TNFRSF1A signaling pathway that leads to NF-kappa-B activation and is required for cell survival. Acts by enhancing RELA transcriptional activity. |
| Protein Name | Interleukin-1 Receptor-Associated Kinase 1-Binding Protein 1Irak1-Binding Protein 1 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Interleukin-1 Receptor-Associated Kinase 1-Binding Protein 1 antibodyAnti-Irak1-Binding Protein 1 antibodyAnti-IRAK1BP1 antibody |
Information sourced from Uniprot.org