Anti-IQGAP2 antibody (1330-1440) (STJ117587)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal IQGAP2 (1330-1440) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:200-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | IQGAP2 |
| Gene ID | 10788 |
| Uniprot ID | IQGA2_HUMAN |
| Immunogen Region | 1330-1440 |
| Immunogen Sequence | QQEVDHATDMVSRAMIDSRT PEEMKHSQSMIEDAQLPLEQ KKRKIQRNLRTLEQTGHVSS ENKYQDILNEIAKDIRNQRI YRKLRKAELAKLQQTLNALN KKAAFYEEQIN |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1330-1440 of human IQGAP2 (NP_006624.2). |
Additional Info
| Tissue Specificity | Isoform 2 expression is enhanced in testis. |
| Function | Binds to activated CDC42 and RAC1 but does not seem to stimulate their GTPase activity. Associates with calmodulin. |
| Protein Name | Ras Gtpase-Activating-Like Protein Iqgap2 |
| Database Links | Reactome: R-HSA-5626467Reactome: R-HSA-6798695Reactome: R-HSA-9013148Reactome: R-HSA-9013149Reactome: R-HSA-9013408 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Ras Gtpase-Activating-Like Protein Iqgap2 antibodyAnti-IQGAP2 antibody |
Information sourced from Uniprot.org