• Western blot analysis of the lysates from HepG2 cells using IQCB1 antibody.
  • Western blot analysis of SH-SY5Y cells using Nephrocystin-5 Polyclonal Antibody diluted at 1:500
  • Western blot analysis of lysates from K562 cells, using IQCB1 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using Nephrocystin-5 Polyclonal Antibody diluted at 1:500

Anti-IQCB1 antibody (431-480) (STJ94403)

SKU:
STJ94403

Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-IQ calmodulin-binding motif-containing protein 1 (431-480) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:40000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: IQCB1
Gene ID: 9657
Uniprot ID: IQCB1_HUMAN
Immunogen Region: 431-480
Specificity: Nephrocystin-5 Polyclonal Antibody detects endogenous levels of Nephrocystin-5 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from human IQCB1. AA range:431-480
Tissue Specificity Ubiquitously expressed in fetal and adult tissues. Localized to the outer segments and connecting cilia of photoreceptor cells. Up-regulated in a number of primary colorectal and gastric tumors.
Function Involved in ciliogenesis. The function in an early step in cilia formation depends on its association with CEP290/NPHP6. Involved in regulation of the BBSome complex integrity, specifically for presence of BBS2 and BBS5 in the complex, and in ciliary targeting of selected BBSome cargos. May play a role in controlling entry of the BBSome complex to cilia possibly implicating CEP290/NPHP6.
Protein Name Iq Calmodulin-Binding Motif-Containing Protein 1
Nephrocystin-5
P53 And Dna Damage-Regulated Iq Motif Protein
Piq
Database Links Reactome: R-HSA-5620912
Cellular Localisation Cytoplasm
Cytoskeleton
Microtubule Organizing Center
Centrosome
Centriole
Localization To The Centrosome Depends On The Interaction With Cep290/Nphp6
Alternative Antibody Names Anti-Iq Calmodulin-Binding Motif-Containing Protein 1 antibody
Anti-Nephrocystin-5 antibody
Anti-P53 And Dna Damage-Regulated Iq Motif Protein antibody
Anti-Piq antibody
Anti-IQCB1 antibody
Anti-KIAA0036 antibody
Anti-NPHP5 antibody
Anti-OK antibody
Anti-SW-cl.85 antibody

Information sourced from Uniprot.org

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