Anti-INSC antibody (STJA0008272)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human INSC
General Information
| Short Description | Rabbit polyclonal anti-Protein inscuteable homolog for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | INSC |
| Gene ID | 387755 |
| Uniprot ID | INSC_HUMAN |
| Immunogen | Synthesized peptide derived from human INSC |
| Specificity | This antibody detects endogenous levels of INSC at Human, Mouse |
Additional Info
| Function | May function as an adapter linking the Par3 complex to the GPSM1/GPSM2 complex. Involved in spindle orientation during mitosis. May regulate cell proliferation and differentiation in the developing nervous system. May play a role in the asymmetric division of fibroblasts and participate in the process of stratification of the squamous epithelium. |
| Protein Name | Protein Inscuteable Homolog |
| Database Links | |
| Cellular Localisation | CytoplasmCell CortexUniformly Distributed In The Cytoplasm During InterphaseDuring MetaphaseDetected In The Cell CortexAdjacent To The Mitotic Spindle Poles |
| Alternative Antibody Names | Anti-Protein Inscuteable Homolog antibodyAnti-INSC antibody |
Information sourced from Uniprot.org