Anti-INS antibody (1-110) (STJ24210)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal INS (1-110) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.09% Sodium Azide, 50% Glycerol, pH7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | INS |
| Gene ID | 3630 |
| Uniprot ID | INS_HUMAN |
| Immunogen Region | 1-110 |
| Immunogen Sequence | MALWMRLLPLLALLALWGPD PAAAFVNQHLCGSHLVEALY LVCGERGFFYTPKTRREAED LQVGQVELGGGPGAGSLQPL ALEGSLQKRGIVEQCCTSIC SLYQLENYCN |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human INS (NP_000198.1). |
Additional Info
| Function | Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. |
| Protein Name | Insulin Cleaved Into - Insulin B Chain - Insulin A Chain |
| Database Links | Reactome: R-HSA-210745Reactome: R-HSA-264876Reactome: R-HSA-422085Reactome: R-HSA-422356Reactome: R-HSA-6807878Reactome: R-HSA-6811558Reactome: R-HSA-74713Reactome: R-HSA-74749Reactome: R-HSA-74751Reactome: R-HSA-74752Reactome: R-HSA-77387Reactome: R-HSA-9615017Reactome: R-HSA-9768919Reactome: R-HSA-977225 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Insulin Cleaved Into - Insulin B Chain - Insulin A Chain antibodyAnti-INS antibody |
Information sourced from Uniprot.org