| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000 IHC-P:1:50-1:200 IF/ICC:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | INS |
| Gene ID: | 3630 |
| Uniprot ID: | INS_HUMAN |
| Immunogen Region: | 1-110 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human INS (NP_000198.1). |
| Immunogen Sequence: | MALWMRLLPLLALLALWGPD PAAAFVNQHLCGSHLVEALY LVCGERGFFYTPKTRREAED LQVGQVELGGGPGAGSLQPL ALEGSLQKRGIVEQCCTSIC SLYQLENYCN |
| Function | Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. |
| Protein Name | Insulin Cleaved Into - Insulin B Chain - Insulin A Chain |
| Database Links | Reactome: R-HSA-210745 Reactome: R-HSA-264876 Reactome: R-HSA-422085 Reactome: R-HSA-422356 Reactome: R-HSA-6807878 Reactome: R-HSA-6811558 Reactome: R-HSA-74713 Reactome: R-HSA-74749 Reactome: R-HSA-74751 Reactome: R-HSA-74752 Reactome: R-HSA-77387 Reactome: R-HSA-9615017 Reactome: R-HSA-9768919 Reactome: R-HSA-977225 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Insulin Cleaved Into - Insulin B Chain - Insulin A Chain antibody Anti-INS antibody |
Information sourced from Uniprot.org