Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Inositol polyphosphate-5-phosphatase A is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
INPP5A |
Gene ID: |
3632 |
Uniprot ID: |
I5P1_HUMAN |
Specificity: |
This antibody detects endogenous levels of INPP5A at Human |
Immunogen: |
Synthesized peptide derived from human INPP5A |
Post Translational Modifications | Isoprenylation at Cys-409 is required for localization at the membrane. |
Function | Phosphatase that specifically hydrolyzes the 5-phosphate of inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate, and inositol 1,3,4,5-tetrasphosphate to inositol 1,3,4-trisphosphate. Plays a crucial role in the survival of cerebellar Purkinje cells. |
Protein Name | Inositol Polyphosphate-5-Phosphatase A43 Kda Inositol Polyphosphate 5-PhosphataseType I Inositol 1 -4 -5-Trisphosphate 5-Phosphatase5ptase |
Database Links | Reactome: R-HSA-1855183 |
Cellular Localisation | Cell MembraneLipid-AnchorCell ProjectionDendrite |
Alternative Antibody Names | Anti-Inositol Polyphosphate-5-Phosphatase A antibodyAnti-43 Kda Inositol Polyphosphate 5-Phosphatase antibodyAnti-Type I Inositol 1 -4 -5-Trisphosphate 5-Phosphatase antibodyAnti-5ptase antibodyAnti-INPP5A antibodyAnti-5PTASE antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance