| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Inositol polyphosphate-5-phosphatase A is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | INPP5A |
| Gene ID: | 3632 |
| Uniprot ID: | I5P1_HUMAN |
| Specificity: | This antibody detects endogenous levels of INPP5A at Human |
| Immunogen: | Synthesized peptide derived from human INPP5A |
| Post Translational Modifications | Isoprenylation at Cys-409 is required for localization at the membrane. |
| Function | Phosphatase that specifically hydrolyzes the 5-phosphate of inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate, and inositol 1,3,4,5-tetrasphosphate to inositol 1,3,4-trisphosphate. Plays a crucial role in the survival of cerebellar Purkinje cells. |
| Protein Name | Inositol Polyphosphate-5-Phosphatase A43 Kda Inositol Polyphosphate 5-PhosphataseType I Inositol 1 -4 -5-Trisphosphate 5-Phosphatase5ptase |
| Database Links | Reactome: R-HSA-1855183 |
| Cellular Localisation | Cell MembraneLipid-AnchorCell ProjectionDendrite |
| Alternative Antibody Names | Anti-Inositol Polyphosphate-5-Phosphatase A antibodyAnti-43 Kda Inositol Polyphosphate 5-Phosphatase antibodyAnti-Type I Inositol 1 -4 -5-Trisphosphate 5-Phosphatase antibodyAnti-5ptase antibodyAnti-INPP5A antibodyAnti-5PTASE antibody |
Information sourced from Uniprot.org