Anti-INMT antibody (1-263) (STJ116603)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal INMT (1-263) antibody for use in WB, IF, ICC and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | INMT |
| Gene ID | 11185 |
| Uniprot ID | INMT_HUMAN |
| Immunogen Region | 1-263 |
| Immunogen Sequence | MKGGFTGGDEYQKHFLPRDY LATYYSFDGSPSPEAEMLKF NLECLHKTFGPGGLQGDTLI DIGSGPTIYQVLAACDSFQD ITLSDFTDRNREELEKWLKK EPGAYDWTPAVKFACELEGN SGRWEEKEEKLRAAVKRVLK CDVHLGNPLAPAVLPLADCV LTLLAMECACCSLDAYRAAL CNLASLLKPGGHLVTTVTLR LPSYMVGKREFSCVALEKEE VEQAVLDAGFDIEQLLHSP |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-263 of human INMT (NP_006765.4). |
Additional Info
| Tissue Specificity | Widely expressed. The highest levels were in thyroid, adrenal gland, adult and fetal lung. Intermediate levels in heart, placenta, skeletal muscle, testis, small intestine, pancreas, stomach, spinal cord, lymph node and trachea. Very low levels in adult and fetal kidney and liver, in adult spleen, thymus, ovary, colon and bone marrow. Not expressed in peripheral blood leukocytes and brain. |
| Function | Functions as a thioether S-methyltransferase and is active with a variety of thioethers and the corresponding selenium and tellurium compounds, including 3-methylthiopropionaldehyde, dimethyl selenide, dimethyl telluride, 2-methylthioethylamine, 2-methylthioethanol, methyl-n-propyl sulfide and diethyl sulfide. Plays an important role in the detoxification of selenium compounds. Catalyzes the N-methylation of tryptamine and structurally related compounds. |
| Protein Name | Indolethylamine N-MethyltransferaseIndolamine N-MethyltransferaseAromatic Alkylamine N-MethyltransferaseAmine N-MethyltransferaseArylamine N-MethyltransferaseThioether S-MethyltransferaseTemt |
| Database Links | Reactome: R-HSA-2408552 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Indolethylamine N-Methyltransferase antibodyAnti-Indolamine N-Methyltransferase antibodyAnti-Aromatic Alkylamine N-Methyltransferase antibodyAnti-Amine N-Methyltransferase antibodyAnti-Arylamine N-Methyltransferase antibodyAnti-Thioether S-Methyltransferase antibodyAnti-Temt antibodyAnti-INMT antibody |
Information sourced from Uniprot.org