Anti-Inhibin alpha antibody [SM4993] (STJA0004993)

SKU:
STJA0004993-50

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Host: Mouse
Applications: IHC/IF
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Inhibin alpha is suitable for use in Immunohistochemistry and Immunofluorescence research applications.
Clonality: Monoclonal
Clone ID: SM4993
Conjugation: Unconjugated
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Dilution Range: IHC/IF (H) 1:200-1:500
Storage Instruction: Store at-20C for up to one year, and avoid repeated freeze-thaw cycles.
Gene Symbol: INHA
Gene ID: 3623
Uniprot ID: INHA_HUMAN
Immunogen: Synthesized peptide derived from human Inhibin A (INHA)
Post Translational Modifications Proteolytic processing yields a number of bioactive forms. The 20/23 kDa forms consist solely of the mature alpha chain, the 26/29 kDa forms consist of the most N-terminal propeptide linked through a disulfide bond to the mature alpha chain, the 50/53 kDa forms encompass the entire proprotein. Each type can be furthermore either mono- or diglycosylated, causing the mass difference.
Function Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
Protein Name Inhibin Alpha Chain
Database Links Reactome: R-HSA-1502540
Reactome: R-HSA-201451
Reactome: R-HSA-209822
Reactome: R-HSA-9839406
Cellular Localisation Secreted
Alternative Antibody Names Anti-Inhibin Alpha Chain antibody
Anti-INHA antibody

Information sourced from Uniprot.org

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