Anti-INA antibody (13-300) (STJ24201)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal INA (13-300) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | INA |
| Gene ID | 9118 |
| Uniprot ID | AINX_HUMAN |
| Immunogen Region | 13-300 |
| Immunogen Sequence | SSYRKVFGDGSRLSARLSGA GGAGGFRSQSLSRSNVASSA ACSSASSLGLGLAYRRPPAS DGLDLSQAAARTNEYKIIRT NEKEQLQGLNDRFAVFIEKV HQLETQNRALEAELAALRQR HAEPSRVGELFQRELRDLRA QLEEASSARSQALLERDGLA EEVQRLRARCEEESRGREGA ERALKAQQRDVDGATLARLD LEKKVESLLDELAFVRQVHD EEVAELLATLQASSQAAAE |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 13-300 of human Alpha Internexin (Q16352). |
Additional Info
| Tissue Specificity | Found predominantly in adult CNS. |
| Post Translational Modifications | O-glycosylated. |
| Function | Class-IV neuronal intermediate filament that is able to self-assemble. It is involved in the morphogenesis of neurons. It may form an independent structural network without the involvement of other neurofilaments or it may cooperate with NEFL to form the filamentous backbone to which NEFM and NEFH attach to form the cross-bridges. May also cooperate with the neuronal intermediate filament protein PRPH to form filamentous networks. |
| Protein Name | Alpha-InternexinAlpha-Inx66 Kda Neurofilament ProteinNf-66Neurofilament-66Neurofilament 5 |
| Database Links | |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Alpha-Internexin antibodyAnti-Alpha-Inx antibodyAnti-66 Kda Neurofilament Protein antibodyAnti-Nf-66 antibodyAnti-Neurofilament-66 antibodyAnti-Neurofilament 5 antibodyAnti-INA antibodyAnti-NEF5 antibody |
Information sourced from Uniprot.org