| Short Description : | Rabbit polyclonal anti-Protein ILRUN (80-130 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ILRUN |
| Gene ID: | 64771 |
| Uniprot ID: | ILRUN_HUMAN |
| Immunogen: | Synthesized peptide derived from the human CF106 at the amino acid range 80-130 |
| Immunogen Region: | 80-130 aa |
| Specificity: | This antibody detects endogenous levels of CF106 at Human/Mouse |
| Function | Negative regulator of innate antiviral response. Blocks IRF3-dependent cytokine production such as IFNA, IFNB and TNF. Interacts with IRF3 and inhibits IRF3 recruitment to type I IFN promoter sequences while also reducing nuclear levels of the coactivators EP300 and CREBBP. |
| Protein Name | Protein IlrunInflammation And Lipid Regulator With Uba-Like And Nbr1-Like Domains Protein |
| Database Links | |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Protein Ilrun antibodyAnti-Inflammation And Lipid Regulator With Uba-Like And Nbr1-Like Domains Protein antibodyAnti-ILRUN antibodyAnti-C6orf106 antibody |
Information sourced from Uniprot.org
