Anti-IL9 antibody {ABflo® 594} (STJ11108645)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationABflo® 594
IsotypeIgG
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
General Information
| Short Description | Rabbit monoclonal IL9 antibody for use in IF, ICC and FC in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IF/ICC/FC |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Isotype | IgG |
| Conjugation | ABflo® 594 |
| Purification | Affinity purification |
| Dilution Range | IF/ICC, 1:50-1:200|FC (intra) , 5 Mu l per 10^6 cells in 100 Mu l volume |
| Formulation | PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis) , pH 7.3. |
| Storage Instruction | Store at 4°C for up to 1 year from the date of receipt. Do not freeze. |
Target Information
| Gene Symbol | IL9 |
| Gene ID | 3578 |
| Uniprot ID | IL9_HUMAN |
| Immunogen | Recombinant protein (or fragment).This information is considered to be commercially sensitive. |
Additional Info
| Function | Multifunctional cytokine secreted mainly by T-helper 2 lymphocytes and also mast cells or NKT cells that plays important roles in the immune response against parasites. Affects intestinal epithelial permeability and adaptive immunity. In addition, induces the differentiation of specific T-cell subsets such as IL-17 producing helper T-cells (TH17) and also proliferation and differentiation of mast cells. Mechanistically, exerts its biological effects through a receptor composed of IL9R subunit and a signal transducing subunit IL2RG. Receptor stimulation results in the rapid activation of JAK1 and JAK3 kinase activities leading to STAT1, STAT3 and STAT5-mediated transcriptional programs. Induction of differentiation genes seems to be mediated by STAT1 alone, while protection of cells from apoptosis depends on STAT3 and STAT5. |
| Protein Name | Interleukin-9Il-9Cytokine P40T-Cell Growth Factor P40 |
| Database Links | Reactome: R-HSA-8985947 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Interleukin-9 antibodyAnti-Il-9 antibodyAnti-Cytokine P40 antibodyAnti-T-Cell Growth Factor P40 antibodyAnti-IL9 antibody |
Information sourced from Uniprot.org