• Immunohistochemistry analysis of paraffin-embedded human stomach cancer using IL9 antibody (STJ24196) at dilution of 1:200 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of paraffin-embedded human colon cancer using IL9 antibody (STJ24196) at dilution of 1:200 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of paraffin-embedded rat lung using IL9 antibody (STJ24196) at dilution of 1:200 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.

Anti-IL9 antibody (19-144) (STJ24196)

SKU:
STJ24196

£169.50 - £449.50
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Host: Rabbit
Applications: WB/IHC
Reactivity: Human/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-IL9 (19-144) is suitable for use in Western Blot and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
IHC-P 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: IL9
Gene ID: 3578
Uniprot ID: IL9_HUMAN
Immunogen Region: 19-144
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 19-144 of human IL9 (NP_000581.1).
Immunogen Sequence: QGCPTLAGILDINFLINKMQ EDPASKCHCSANVTSCLCLG IPSDNCTRPCFSERLSQMTN TTMQTRYPLIFSRVKKSVEV LKNNKCPYFSCEQPCNQTTA GNALTFLKSLLEIFQKEKMR GMRGKI
Function Multifunctional cytokine secreted mainly by T-helper 2 lymphocytes and also mast cells or NKT cells that plays important roles in the immune response against parasites. Affects intestinal epithelial permeability and adaptive immunity. In addition, induces the differentiation of specific T-cell subsets such as IL-17 producing helper T-cells (TH17) and also proliferation and differentiation of mast cells. Mechanistically, exerts its biological effects through a receptor composed of IL9R subunit and a signal transducing subunit IL2RG. Receptor stimulation results in the rapid activation of JAK1 and JAK3 kinase activities leading to STAT1, STAT3 and STAT5-mediated transcriptional programs. Induction of differentiation genes seems to be mediated by STAT1 alone, while protection of cells from apoptosis depends on STAT3 and STAT5.
Protein Name Interleukin-9
Il-9
Cytokine P40
T-Cell Growth Factor P40
Database Links Reactome: R-HSA-8985947
Cellular Localisation Secreted
Alternative Antibody Names Anti-Interleukin-9 antibody
Anti-Il-9 antibody
Anti-Cytokine P40 antibody
Anti-T-Cell Growth Factor P40 antibody
Anti-IL9 antibody

Information sourced from Uniprot.org

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