Anti-IL5 antibody (C-Term) (STJA0010194)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from C-ternal mouse IL5
General Information
| Short Description | Rabbit polyclonal anti-IL5 (C-Term) for use in WB and ELISA in Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:1000-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | Il5 |
| Gene ID | 16191 |
| Uniprot ID | IL5_MOUSE |
| Immunogen | Synthesized peptide derived from C-ternal mouse IL5 |
| Immunogen Region | C-Term |
| Specificity | This antibody detects endogenous levels of Mouse IL5 |
Additional Info
| Function | Homodimeric cytokine expressed predominantly by T-lymphocytes and NK cells that plays an important role in the survival, differentiation, and chemotaxis of eosinophils. Also acts on activated and resting B-cells to induce immunoglobulin production, growth, and differentiation. Mechanistically, exerts its biological effects through a receptor composed of IL5RA subunit and the cytokine receptor common subunit beta/CSF2RB. Binding to the receptor leads to activation of various kinases including LYN, SYK and JAK2 and thereby propagates signals through the RAS-MAPK and JAK-STAT5 pathways respectively. |
| Protein Name | Interleukin-5Il-5B-Cell Growth Factor IiBcgf-IiCytotoxic T-Lymphocyte InducerEosinophil Differentiation FactorT-Cell Replacing FactorTrf |
| Database Links | Reactome: R-MMU-512988Reactome: -MMU-5673001Reactome: -MMU-912526 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Interleukin-5 antibodyAnti-Il-5 antibodyAnti-B-Cell Growth Factor Ii antibodyAnti-Bcgf-Ii antibodyAnti-Cytotoxic T-Lymphocyte Inducer antibodyAnti-Eosinophil Differentiation Factor antibodyAnti-T-Cell Replacing Factor antibodyAnti-Trf antibodyAnti-Il5 antibodyAnti-Il-5 antibody |
Information sourced from Uniprot.org