Anti-IL38/IL1F10 antibody [M3] (STJA0022273)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2a
General Information
| Short Description | Mouse monoclonal Interleukin-1 Family Member 10 antibody for use in ELISA and Neut in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/Neut |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS |
Product Properties
| Clonality | Monoclonal |
| Clone ID | M3 |
| Isotype | IgG2a |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Protein A/G purified from cell culture supernatant |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months |
Target Information
| Gene Symbol | IL1F10 |
| Gene ID | 84639 |
| Uniprot ID | IL1FA_HUMAN |
Additional Info
| Function | Cytokine with immunomodulatory activity. Alone, does not induce cytokine production, but reduces IL22 and IL17A production by T-cells in response to heat-killed Candida albicans. Reduces IL36G-induced production of IL8 by peripheral blood mononuclear cells. Increases IL6 production by dendritic cells stimulated by bacterial lipopolysaccharides (LPS). Ligand for IL-36R/IL1RL2. |
| Protein Name | Interleukin-1 Family Member 10Il-1f10Family Of Interleukin 1-ThetaFil1 ThetaInterleukin-1 Hy2Il-1hy2Interleukin-1 ThetaIl-1 ThetaInterleukin-38Il-38 |
| Database Links | Reactome: R-HSA-9007892Reactome: R-HSA-9014826 |
| Cellular Localisation | CytoplasmSecretedThe Secretion Is Dependent On Protein Unfolding And Facilitated By The Cargo Receptor Tmed10It Results In Protein Translocation From The Cytoplasm Into The Ergic (Endoplasmic Reticulum-Golgi Intermediate Compartment) Followed By Vesicle Entry And Secretion |
| Alternative Antibody Names | Anti-Interleukin-1 Family Member 10 antibodyAnti-Il-1f10 antibodyAnti-Family Of Interleukin 1-Theta antibodyAnti-Fil1 Theta antibodyAnti-Interleukin-1 Hy2 antibodyAnti-Il-1hy2 antibodyAnti-Interleukin-1 Theta antibodyAnti-Il-1 Theta antibodyAnti-Interleukin-38 antibodyAnti-Il-38 antibodyAnti-IL1F10 antibodyAnti-FIL1T antibodyAnti-IL1HY2 antibodyAnti-IL38 antibodyAnti-FKSG75 antibodyAnti-UNQ6119 antibodyAnti-PRO20041 antibody |
Information sourced from Uniprot.org