Anti-IL34 antibody [1D12] (STJ98173)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenPurified recombinant fragment of human IL-34 expressed in E. Coli.
General Information
| Short Description | Mouse monoclonal anti-Interleukin-34 for use in WB, IF, FC and ELISA in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/FC/ELISA |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 1D12 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Purification | Affinity purification |
| Dilution Range | WB 1:500-1:2000IF 1:200-1:1000FC 1:200-1:400ELISA 1:10000 |
| Formulation | Liquid in PBS containing 0.03% Sodium Azide, 0.5% BSA, 50% Glycerol. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | IL34 |
| Gene ID | 146433 |
| Uniprot ID | IL34_HUMAN |
| Immunogen | Purified recombinant fragment of human IL-34 expressed in E. Coli. |
| Specificity | IL-34 Monoclonal Antibody detects endogenous levels of IL-34 protein. |
Additional Info
| Function | Cytokine that promotes the proliferation, survival and differentiation of monocytes and macrophages. Promotes the release of pro-inflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, and in the regulation of bone resorption. Signaling via CSF1R and its downstream effectors stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1. |
| Protein Name | Interleukin-34Il-34 |
| Database Links | Reactome: R-HSA-449836Reactome: R-HSA-9680350 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Interleukin-34 antibodyAnti-Il-34 antibodyAnti-IL34 antibodyAnti-C16orf77 antibody |
Information sourced from Uniprot.org