Anti-IL31RA antibody [SAA0825] {PE} (STJA0031562)
SPECIFICATIONS
ClonalityMonoclonal
HostHuman
ConjugationPE
IsotypeIgG2k
General Information
| Short Description | Human monoclonal Interleukin-31 Receptor Subunit Alpha antibody for use in ELISA and FC in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/FC |
| Host | Human |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SAA0825 |
| Isotype | IgG2k |
| Conjugation | PE |
| Concentration | 0.5 mg/mL |
| Purification | Purified |
| Formulation | PBS pH 7.4, 50% glycerol, 0.05% proclin300 |
| Storage Instruction | Store at 4°C for 12 months. Protect from light. Do not freeze. |
Target Information
| Gene Symbol | IL31RA |
| Gene ID | 133396 |
| Uniprot ID | IL31R_HUMAN |
Additional Info
| Post Translational Modifications | N-glycosylated. |
| Function | Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5. May function in skin immunity. Mediates IL31-induced itch, probably in a manner dependent on cation channels TRPA1 and TRPV1. Positively regulates numbers and cycling status of immature subsets of myeloid progenitor cells in bone marrow in vivo and enhances myeloid progenitor cell survival in vitro. |
| Protein Name | Interleukin-31 Receptor Subunit AlphaIl-31 Receptor Subunit AlphaIl-31r Subunit AlphaIl-31r-AlphaIl-31raCytokine Receptor-Like 3Glm-RHglm-RGp130-Like Monocyte ReceptorGp130-Like ReceptorZcytor17 |
| Database Links | Reactome: R-HSA-6788467 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinPresynaptic Cell MembraneCell ProjectionAxon |
| Alternative Antibody Names | Anti-Interleukin-31 Receptor Subunit Alpha antibodyAnti-Il-31 Receptor Subunit Alpha antibodyAnti-Il-31r Subunit Alpha antibodyAnti-Il-31r-Alpha antibodyAnti-Il-31ra antibodyAnti-Cytokine Receptor-Like 3 antibodyAnti-Glm-R antibodyAnti-Hglm-R antibodyAnti-Gp130-Like Monocyte Receptor antibodyAnti-Gp130-Like Receptor antibodyAnti-Zcytor17 antibodyAnti-IL31RA antibodyAnti-CRL3 antibodyAnti-GPL antibodyAnti-UNQ6368 antibodyAnti-PRO21073 antibodyAnti-PRO21384 antibody |
Information sourced from Uniprot.org