![Anti-IL23R nanobody [SAA1299] (STJN000282)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/200895/413077/STJN000282-SDS-PAGE-1__80941.1749232583.jpg?c=1 "Anti-IL23R nanobody [SAA1299] (STJN000282)")
![Anti-IL23R nanobody [SAA1299] (STJN000282)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/200895/413077/STJN000282-SDS-PAGE-1__80941.1749232583.jpg?c=1 "Anti-IL23R nanobody [SAA1299] (STJN000282)")
Anti-IL23R nanobody [SAA1299] (STJN000282)
SPECIFICATIONS
ClonalityMonoclonal
HostAlpaca
ConjugationUnconjugated
IsotypeVHH-8His-Cys-tag
General Information
| Short Description | Alpaca monoclonal nanobody anti-Interleukin-23 Receptor is suitable for use in ELISA, Flow Cytometry and SPR research applications. |
| Applications | ELISA/FC/SPR |
| Host | Alpaca |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SAA1299 |
| Isotype | VHH-8His-Cys-tag |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Purified by Nickel column. |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term. |
Target Information
| Gene Symbol | IL23R |
| Gene ID | 149233 |
| Uniprot ID | IL23R_HUMAN |
Additional Info
| Post Translational Modifications | Phosphorylated in response to IL23. |
| Function | Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis. |
| Protein Name | Interleukin-23 ReceptorIl-23 ReceptorIl-23r |
| Database Links | Reactome: R-HSA-6785807Reactome: R-HSA-9020933 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Nanobody Names | Anti-Interleukin-23 Receptor nanobodyAnti-Il-23 Receptor nanobodyAnti-Il-23r nanobodyAnti-IL23R nanobody |
Information sourced from Uniprot.org