Anti-IL1RL2 antibody (330-410 aa) (STJ190334)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 330-410
General Information
| Short Description | Rabbit polyclonal anti-Interleukin-1 receptor-like 2 (330-410 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | IL1RL2 |
| Gene ID | 8808 |
| Uniprot ID | ILRL2_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 330-410 |
| Immunogen Region | 330-410 aa |
| Specificity | ILRL2 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways. The IL-36 signaling system is thought to be present in epithelial barriers and to take part in local inflammatory response.it is similar to the IL-1 system. Seems to be involved in skin inflammatory response by induction of the IL-23/IL-17/IL-22 pathway. |
| Protein Name | Interleukin-1 Receptor-Like 2Il-36 ReceptorIl-36rInterleukin-1 Receptor-Related Protein 2Il-1rrp2Il1r-Rp2 |
| Database Links | Reactome: R-HSA-9007892Reactome: R-HSA-9014826 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Interleukin-1 Receptor-Like 2 antibodyAnti-Il-36 Receptor antibodyAnti-Il-36r antibodyAnti-Interleukin-1 Receptor-Related Protein 2 antibodyAnti-Il-1rrp2 antibodyAnti-Il1r-Rp2 antibodyAnti-IL1RL2 antibodyAnti-IL1RRP2 antibody |
Information sourced from Uniprot.org