Anti-IL1F10 antibody (101-150 aa) (STJ97678)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from Interleukin-1 family member 10 at the amino acid range 101-150
STJ97678
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General Information

Short DescriptionRabbit polyclonal anti-Interleukin-1 family member 10 (101-150 aa) for use in WB, IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/IHC/IF/ELISA
HostRabbit
ReactivityHuman/Rat/Mouse
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
Concentration1 mg/mL
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution RangeWB 1:500-1:2000
IHC-P 1:100-1:300
ELISA 1:10000
IF 1:50-200
FormulationLiquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage InstructionStore at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolIL1F10
Gene ID84639
Uniprot IDIL1FA_HUMAN
ImmunogenSynthesized peptide derived from Interleukin-1 family member 10 at the amino acid range 101-150
Immunogen Region101-150 aa
SpecificityIL-1F10 Polyclonal Antibody detects endogenous levels of IL-1F10 protein.

Additional Info

Function Cytokine with immunomodulatory activity. Alone, does not induce cytokine production, but reduces IL22 and IL17A production by T-cells in response to heat-killed Candida albicans. Reduces IL36G-induced production of IL8 by peripheral blood mononuclear cells. Increases IL6 production by dendritic cells stimulated by bacterial lipopolysaccharides (LPS). Ligand for IL-36R/IL1RL2.
Protein Name Interleukin-1 Family Member 10
Il-1f10
Family Of Interleukin 1-Theta
Fil1 Theta
Interleukin-1 Hy2
Il-1hy2
Interleukin-1 Theta
Il-1 Theta
Interleukin-38
Il-38
Database Links Reactome: R-HSA-9007892
Reactome: R-HSA-9014826
Cellular Localisation Cytoplasm
Secreted
The Secretion Is Dependent On Protein Unfolding And Facilitated By The Cargo Receptor Tmed10
It Results In Protein Translocation From The Cytoplasm Into The Ergic (Endoplasmic Reticulum-Golgi Intermediate Compartment) Followed By Vesicle Entry And Secretion
Alternative Antibody Names Anti-Interleukin-1 Family Member 10 antibody
Anti-Il-1f10 antibody
Anti-Family Of Interleukin 1-Theta antibody
Anti-Fil1 Theta antibody
Anti-Interleukin-1 Hy2 antibody
Anti-Il-1hy2 antibody
Anti-Interleukin-1 Theta antibody
Anti-Il-1 Theta antibody
Anti-Interleukin-38 antibody
Anti-Il-38 antibody
Anti-IL1F10 antibody
Anti-FIL1T antibody
Anti-IL1HY2 antibody
Anti-IL38 antibody
Anti-FKSG75 antibody
Anti-UNQ6119 antibody
Anti-PRO20041 antibody

Information sourced from Uniprot.org

Citations

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