Anti-IL17RE antibody (STJA0008102)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human IL-17RE
General Information
| Short Description | Rabbit polyclonal anti-Interleukin-17 receptor E for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | IL17RE |
| Gene ID | 132014 |
| Uniprot ID | I17RE_HUMAN |
| Immunogen | Synthesized peptide derived from human IL-17RE |
| Specificity | This antibody detects endogenous levels of IL-17RE at Human, Mouse, Rat |
Additional Info
| Function | Specific functional receptor for IL17C. May be signaling through the NF-kappa-B and MAPK pathways. May require TRAF3IP2 /ACT1 for signaling. May be a crucial regulator in innate immunity to bacterial pathogens. Isoform 2 and isoform 4 may be either cytoplasmic inactive or dominant active forms. Isoform 3 and isoform 5 may act as soluble decoy receptors. |
| Protein Name | Interleukin-17 Receptor EIl-17 Receptor EIl-17re |
| Database Links | Reactome: R-HSA-448424 |
| Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 2: CytoplasmIsoform 3: SecretedIsoform 4: CytoplasmIsoform 5: Secreted |
| Alternative Antibody Names | Anti-Interleukin-17 Receptor E antibodyAnti-Il-17 Receptor E antibodyAnti-Il-17re antibodyAnti-IL17RE antibodyAnti-UNQ3056 antibodyAnti-PRO9877 antibody |
Information sourced from Uniprot.org