| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Goat polyclonal antibody anti-IL13RA2 (96-107) is suitable for use in ELISA and Western Blot research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:128000. WB: Approx 50+60kDa bands observed in lysates of cell line HeLa (calculated MW of 44.2kDa according to NP_000631.1). The observed molecular weight corresponds to earlier findings in liter |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | IL13RA2 |
| Gene ID: | 3598 |
| Uniprot ID: | I13R2_HUMAN |
| Immunogen Region: | 96-107 |
| Accession Number: | NP_000631.1 |
| Immunogen Sequence: | DLNKGIEAKIHT |
| Function | Cell surface receptor that plays a role in the regulation of IL-13-mediated responses. Functions as a decoy receptor that inhibits IL-13- and IL-4-mediated signal transduction via the JAK-STAT pathway and thereby modulates immune responses and inflammation. Serves as a functional signaling receptor for IL-13 in an alternative pathway involving AP-1 ultimately leading to the production of TGFB1. |
| Protein Name | Interleukin-13 Receptor Subunit Alpha-2 Il-13 Receptor Subunit Alpha-2 Il-13r Subunit Alpha-2 Il-13r-Alpha-2 Il-13ra2 Interleukin-13-Binding Protein Cd Antigen Cd213a2 |
| Database Links | Reactome: R-HSA-6785807 |
| Cellular Localisation | Cell Membrane Single-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Interleukin-13 Receptor Subunit Alpha-2 antibody Anti-Il-13 Receptor Subunit Alpha-2 antibody Anti-Il-13r Subunit Alpha-2 antibody Anti-Il-13r-Alpha-2 antibody Anti-Il-13ra2 antibody Anti-Interleukin-13-Binding Protein antibody Anti-Cd Antigen Cd213a2 antibody Anti-IL13RA2 antibody Anti-IL13R antibody |
Information sourced from Uniprot.org
