Anti-IL13RA1 antibody (29-427) (STJ28711)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal IL13RA1 (29-427) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | IL13RA1 |
| Gene ID | 3597 |
| Uniprot ID | I13R1_HUMAN |
| Immunogen Region | 29-427 |
| Immunogen Sequence | TETQPPVTNLSVSVENLCTV IWTWNPPEGASSNCSLWYFS HFGDKQDKKIAPETRRSIEV PLNERICLQVGSQCSTNESE KPSILVEKCISPPEGDPESA VTELQCIWHNLSYMKCSWLP GRNTSPDTNYTLYYWHRSLE KIHQCENIFREGQYFGCSFD LTKVKDSSFEQHSVQIMVKD NAGKIKPSFNIVPLTSRVKP DPPHIKNLSFHNDDLYVQWE NPQNFISRCLFYEVEVNNS |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 29-343 of human IL13RA1 (NP_001551.1). |
Additional Info
| Tissue Specificity | Ubiquitous. Highest levels in heart, liver, skeletal muscle and ovary.lowest levels in brain, lung and kidney. Also found in B-cells, T-cells and endothelial cells. |
| Function | Binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity. |
| Protein Name | Interleukin-13 Receptor Subunit Alpha-1Il-13 Receptor Subunit Alpha-1Il-13r Subunit Alpha-1Il-13r-Alpha-1Il-13ra1Cancer/Testis Antigen 19Ct19Cd Antigen Cd213a1 |
| Database Links | Reactome: R-HSA-6785807 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Interleukin-13 Receptor Subunit Alpha-1 antibodyAnti-Il-13 Receptor Subunit Alpha-1 antibodyAnti-Il-13r Subunit Alpha-1 antibodyAnti-Il-13r-Alpha-1 antibodyAnti-Il-13ra1 antibodyAnti-Cancer/Testis Antigen 19 antibodyAnti-Ct19 antibodyAnti-Cd Antigen Cd213a1 antibodyAnti-IL13RA1 antibodyAnti-IL13R antibodyAnti-IL13RA antibody |
Information sourced from Uniprot.org