Anti-IL-2RB antibody (27-235 aa) [SRM5442] (STJ11107355)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal IL-2RB (27-235 aa) antibody for use in IF, ICC and ELISA in mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SRM5442 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | IF/ICC:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.09% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | Il2rb |
| Gene ID | 16185 |
| Uniprot ID | IL2RB_MOUSE |
| Immunogen Region | 27-235 aa |
| Immunogen Sequence | AVKNCSHLECFYNSRANVSC MWSHEEALNVTTCHVHAKSN LRHWNKTCELTLVRQASWAC NLILGSFPESQSLTSVDLLD INVVCWEEKGWRRVKTCDFH PFDNLRLVAPHSLQVLHIDT QRCNISWKVSQVSHYIEPYL EFEARRRLLGHSWEDASVLS LKQRQQWLFLEMLIPSTSYE VQVRVKAQRNNTGTWSPWSQ PLTFRTRPA |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 27-235 of mouse IL-2RB (NP_032394.1). |
Additional Info
| Function | Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15. |
| Protein Name | Interleukin-2 Receptor Subunit BetaIl-2 Receptor Subunit BetaIl-2r Subunit BetaIl-2rbHigh Affinity Il-2 Receptor Subunit BetaP70-75Cd Antigen Cd122 |
| Database Links | Reactome: R-MMU-5673001Reactome: -MMU-8983432Reactome: -MMU-9020558Reactome: -MMU-912526 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinCell Surface |
| Alternative Antibody Names | Anti-Interleukin-2 Receptor Subunit Beta antibodyAnti-Il-2 Receptor Subunit Beta antibodyAnti-Il-2r Subunit Beta antibodyAnti-Il-2rb antibodyAnti-High Affinity Il-2 Receptor Subunit Beta antibodyAnti-P70-75 antibodyAnti-Cd Antigen Cd122 antibodyAnti-Il2rb antibody |
Information sourced from Uniprot.org