Anti-IL-1RA antibody (27-178) [S5266RM] (STJ11105266)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal IL-1RA (27-178) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S5266RM |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1000-1:5000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | Il1rn |
| Gene ID | 16181 |
| Uniprot ID | IL1RA_MOUSE |
| Immunogen Region | 27-178 |
| Immunogen Sequence | PSGKRPCKMQAFRIWDTNQK TFYLRNNQLIAGYLQGPNIK LEEKIDMVPIDLHSVFLGIH GGKLCLSCAKSGDDIKLQLE EVNITDLSKNKEEDKRFTFI RSEKGPTTSFESAACPGWFL CTTLEADRPVSLTNTPEEPL IVTKFYFQEDQ |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 27-178 of mouse IL-1RA ( NP_001034790.1). |
Additional Info
| Function | Anti-inflammatory antagonist of interleukin-1 family of proinflammatory cytokines such as interleukin-1beta/IL1B and interleukin-1alpha/IL1A. Protects from immune dysregulation and uncontrolled systemic inflammation triggered by IL1 for a range of innate stimulatory agents such as pathogens. |
| Protein Name | Interleukin-1 Receptor Antagonist ProteinIl-1rnIl-1raIrapIl1 Inhibitor |
| Database Links | Reactome: R-MMU-9020702 |
| Cellular Localisation | Isoform 1: SecretedIsoform 2: Cytoplasm |
| Alternative Antibody Names | Anti-Interleukin-1 Receptor Antagonist Protein antibodyAnti-Il-1rn antibodyAnti-Il-1ra antibodyAnti-Irap antibodyAnti-Il1 Inhibitor antibodyAnti-Il1rn antibodyAnti-Il-1ra antibody |
Information sourced from Uniprot.org