Anti-IL-18BP antibody [R31-4Z-6] (STJA0035607)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human IL18 binding protein
General Information
| Short Description | Rabbit monoclonal anti-IL-18BP for use in WB and IHC-P in Human and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P |
| Host | Rabbit |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R31-4Z-6 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Chromatography |
| Dilution Range | WB 1:500-1:1000IHC 1:100-1:200 |
| Formulation | Liquid in PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | IL18BP |
| Gene ID | 10068 |
| Uniprot ID | I18BP_HUMAN |
| Immunogen | A synthesized peptide derived from human IL18 binding protein |
Additional Info
| Tissue Specificity | Strongly expressed in heart, lung, placenta and spleen. |
| Post Translational Modifications | N- and O-glycosylated. O-glycosylated with core 1-like and core 2-like glycans. O-glycan heterogeneity at Ser-53: HexHexNAc (major) and Hex2HexNAc2 (minor). N-glycan heterogeneity at Asn-103: Hex5HexNAc4 (minor), dHex1Hex5HexNAc4 (major) and Hex6HexNAc5 (minor).N-glycan at Asn-147: dHex1Hex5HexNAc4. |
| Function | Isoform A binds to IL-18 and inhibits its activity. Functions as an inhibitor of the early TH1 cytokine response. |
| Protein Name | Interleukin-18-Binding ProteinIl-18bpTadekinig-Alfa |
| Database Links | Reactome: R-HSA-9008059Reactome: R-HSA-9012546 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Interleukin-18-Binding Protein antibodyAnti-Il-18bp antibodyAnti-Tadekinig-Alfa antibodyAnti-IL18BP antibody |
Information sourced from Uniprot.org