Anti-IL-1 Receptor Antagonist Protein-Tag antibody [R01-6J5] (STJA0034467)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide of human IL1RA
General Information
| Short Description | Rabbit monoclonal anti-IL-1 Receptor Antagonist Protein-Tag for use in WB, IHC-F, IHC-P, ICC, IF and IP in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-F/IHC-P/ICC/IF/IP |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R01-6J5 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100IF 1:50-1:200IP 1:20 |
| Formulation | 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | IL1RN |
| Gene ID | 3557 |
| Uniprot ID | IL1RA_HUMAN |
| Immunogen | A synthetic peptide of human IL1RA |
Additional Info
| Tissue Specificity | The intracellular form of IL1RN is predominantly expressed in epithelial cells. |
| Function | Anti-inflammatory antagonist of interleukin-1 family of proinflammatory cytokines such as interleukin-1beta/IL1B and interleukin-1alpha/IL1A. Protects from immune dysregulation and uncontrolled systemic inflammation triggered by IL1 for a range of innate stimulatory agents such as pathogens. |
| Protein Name | Interleukin-1 Receptor Antagonist ProteinIl-1rnIl-1raIrapIcil-1raIl1 InhibitorAnakinra |
| Database Links | Reactome: R-HSA-6783783Reactome: R-HSA-9020702 |
| Cellular Localisation | Isoform 1: SecretedIsoform 2: CytoplasmIsoform 3: CytoplasmIsoform 4: Cytoplasm |
| Alternative Antibody Names | Anti-Interleukin-1 Receptor Antagonist Protein antibodyAnti-Il-1rn antibodyAnti-Il-1ra antibodyAnti-Irap antibodyAnti-Icil-1ra antibodyAnti-Il1 Inhibitor antibodyAnti-Anakinra antibodyAnti-IL1RN antibodyAnti-IL1F3 antibodyAnti-IL1RA antibody |
Information sourced from Uniprot.org